The results of 20 years of large-scale registration showed that diabetes was not associated with a risk of rupture of abdominal aortic aneurysms

Surprisingly, numerous studies have shown that diabetes has a protective effect on the occurrence and progression of abdominal aortic aneurysms, the mechanism of which is still unknown.
the purpose of this study is to explore whether the protective effect of diabetes on abdominal aortic aneurysms extends to abdominal aortic rupture.
method This is a registry-based case-control study.
patients with ruptured abdominal aortic aneurysms were paired 1:1 with patients undergoing selected surgery, depending on the patient's gender, age and year of diagnosis.
the advantage ratio of diabetes diagnosis to abdominal aortic aneurysm rupture (OR) was assessed using multi-conditional logistic regression analysis.
6,293 patients with a potential abdominal aortic aneurysm rupture between 1996 and 2016.
a total of 898 patients with ruptured abdominal aortic aneurysms were excluded because there was no matching control.
, there are 5,395 cases remaining (Figure 1).
of these cases was 75 years, of which 85.4 per cent were male.
rupture of the abdominal aortic aneurysm was negatively related to diabetes, with the original OR value of 0.82 (95% CI 0.71 to 0.95).
when the mixing factor is corrected, the OR value increases to 0.97 (95% CI 0.83 to 1.14).
were strated by age and year of diagnosis, and there was no significant change in the results.
based on gender stratation, women have higher OR values than men (correct OR 1.82; 95% CI 1.17 to 2.81) (Table 1).
1. The correlation between diabetes and R-abdominal aortic aneurysm was 58% in 5,395 patients with a total mortality rate of 30 days (n-3,145).
with Cox regression, the original risk ratio (HR) of 30-day mortality was 1.06 (95% CI 0.93 to 1.22) compared to non-diabetic patients.
, male sex and age had little effect on this estimate (HR 1.11; 95% CI 0.97 to 1.28).
patients with total abdominal aortic aneurysms, no diabetes was found to have a protective effect on abdominal aortic aneurysm rupture.
, diabetes does not increase the risk of death within 30 days of a ruptured abdominal aortic aneurysm.