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The research group of Meng Anming from the School of Life Sciences found that the second polar body of mouse embryos establishes cell fate asymmetry

 Last Update: 2022-01-23
 Source: Internet
 Author: User

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Humans and mammals ovulate periodically, and the released egg is very large, it inherits most of the cytoplasm of the oocyte and a nucleus that retains two sets of chromosomes; at the same time, it also releases a small volume connected to the egg.

The research of Academician Meng Anming's team in mouse models found that the second polar body contains components such as RNA polymerase II and ribosomes involved in gene transcription and mRNA translation

This achievement is the first to discover that the second polar body of mammalian fertilized egg has an important biological function, but the molecular mechanism of its function remains to be further studied

The result was published online on January 10 , 2022 in National under the title " The second polar body contributes to the fate asymmetry in the mouse embryo ".

Paper link: https://doi.

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