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The regulatory role of small GTPases-Rab13 in breast cancer stem cells

 Last Update: 2022-05-18
 Source: Internet
 Author: User

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The "seed" and "soil" theories are the basic theories of cancer stem cells

Legend.

On April 8, 2022 , Assistant Researcher Wang Hui from Jiao Baowei's research group published a research paper online entitled "Rab13 sustains breast cancer stem cells by supporting tumor-stroma crosstalk" in the Nature Index journal "Cancer Research"

Researcher Jiao Baowei is the corresponding author of this work

CD44 is a widely recognized breast cancer stem cell marker, and its splicing variant CD44v is diversely expressed in tumors and is closely associated with poor patient prognosis, but the splicing regulatory mechanism of CD44v production remains unclear

The above work was completed under the funding of the National Key Research and Development Program, the National Natural Science Foundation of China, and the Yunnan Provincial Fund

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