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The production process of Propyl 6-aminopyridazine-3-carboxylate, also known as Propyl 2-[[2-[(4S)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]amino]propanoate, is a complex and multi-step process that involves the synthesis of several intermediate compounds.
The final product is a white to off-white solid that is soluble in organic solvents.
The production process of Propyl 6-aminopyridazine-3-carboxylate can be divided into several steps, including the synthesis of the intermediate compounds, their purification, and the final step of synthesis of the target compound.
The steps involved in the production process are:
- Synthesis of Intermediate Compounds: The synthesis of Propyl 6-aminopyridazine-3-carboxylate involves the synthesis of several intermediate compounds, including 2-[(4S)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-one, Propyl 2-[(4S)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-ylcarboxylate, and Propyl 2-[[2-[(4S)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]amino]propanamide.
- Purification of Intermediate Compounds: The intermediate compounds synthesized in step 1 are purified using various purification techniques, such as crystallization, chromatography, and recrystallization.
The purification step is necessary to remove any impurities that may have been introduced during the synthesis process. - Synthesis of Propyl 6-aminopyridazine-3-carboxylate: The final step in the production process involves the synthesis of Propyl 6-aminopyridazine-3-carboxylate.
This is achieved by subjecting the purified intermediate compounds to appropriate chemical reactions, such as esterification, amination, and hydrolysis. - Characterization of the Final Product: The final product is characterized using various analytical techniques, such as spectroscopy, chromatography, and mass spectrometry.
These techniques are used to confirm the identity and purity of the final product.
In conclusion, the production process of Propyl 6-aminopyridazine-3-carboxylate is a complex and multi-step process that involves the synthesis of several intermediate compounds.
The final product is a white to off-white solid that is soluble in organic solvents and is useful as an intermediate in the synthesis of other compounds.
The production process requires careful purification and characterization of the intermediate and final products to ensure their identity and purity.