The Production Process of 6-BROMO-2,2'-BIPYRIDINE

Introduction:

6-Bromo-2,2'-bipyridine is an organic compound that is commonly used in various chemical reactions.
The production process of 6-bromo-2,2'-bipyridine is a complex process that involves several steps, including the synthesis of the starting materials, the reaction steps, and the purification and isolation of the final product.
In this article, we will discuss the production process of 6-bromo-2,2'-bipyridine, including the various techniques and equipment used in the process.

Synthesis of the Starting Materials:

The production of 6-bromo-2,2'-bipyridine begins with the synthesis of the starting materials, which includes the synthesis of 2,2'-bipyridine and the synthesis of 6-bromo-2,2'-bipyridine.
The synthesis of 2,2'-bipyridine involves the reaction of 2,2'-diaminobiphenyl with chloroform and sodium hydroxide.
The synthesis of 6-bromo-2,2'-bipyridine involves the reaction of 2,2'-bipyridine with bromine.

Chlorination of 2,2'-bipyridine:

After the synthesis of 2,2'-bipyridine, the next step is to chlorinate it.
This involves the addition of chlorine to 2,2'-bipyridine in the presence of a catalyst, such as hydrochloric acid or pyridine.
The reaction produces 2,2'-dichlorobiphenyl, which is further treated with sodium hydroxide to produce 2,2'-bipyridine.

Bromination of 2,2'-bipyridine:

After the chlorination of 2,2'-bipyridine, the next step is to brominate it.
This involves the addition of bromine to 2,2'-bipyridine in the presence of a catalyst, such as aluminum chloride.
The reaction produces 6-bromo-2,2'-bipyridine.

Purification and Isolation of the Final Product:

After the completion of the above steps, the final product, 6-bromo-2,2'-bipyridine, is purified and isolated.
This involves the use of various techniques, such as filtration, crystallization, and distillation.
The purified and isolated 6-bromo-2,2'-bipyridine is then converted into the desired form, such as a solid or a liquid, for storage and transportation.

Conclusion:

The production process of 6-bromo-2,2'-bipyridine is a complex process that involves several steps, including the synthesis of the starting materials, the reaction steps, and the purification and isolation of the final product.
The process requires the use of various equipment and techniques, such as chlorination, bromination, filtration, crystallization, and distillation.
The final product is then converted into the desired form for storage and transportation.
The production of 6-bromo-2,2'-bipyridine is an essential step in the chemical industry, as it is used in various chemical reactions.