 Home > Active Ingredient News > Drugs Articles > The Production Process of 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-, compd. with 2,2′-iminobis[ethanol] (1:1)

The Production Process of 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-, compd. with 2,2′-iminobis[ethanol] (1:1)

 Last Update: 2023-05-11
 Source: Internet
 Author: User

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potassium water retention

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29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-, compd.
with 2,2′-iminobis[ethanol] (1:1) is a complex organic compound that is widely used in various industries, including the chemical, pharmaceutical, and cosmetic industries.
The compound is synthesized through a multi-step process that involves several chemical reactions and purification steps.
The production process of 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-, compd.
with 2,2′-iminobis[ethanol] (1:1) can be broken down into the following steps:

Synthesis of 29-Nordammara-17(20),24-dien-21-oic acid
The synthesis of 29-Nordammara-17(20),24-dien-21-oic acid involves several chemical reactions, including the Friedel-Crafts alkylation, the Wolff-Kishner reduction, and the Wurtz-Fittig dehalogenation.
The synthesis process involves the following steps:

a.
Preparation of the starting material: The synthesis of 29-Nordammara-17(20),24-dien-21-oic acid begins with the preparation of the starting material, which is a mixture of 2-cyclopenten-1-one and 1,4-cyclohexadiene.

b.
Friedel-Crafts alkylation: The mixture of 2-cyclopenten-1-one and 1,4-cyclohexadiene is then treated with a solution of 29-Nordammara-17(20),24-dien-21-oic acid chloride in a solvent such as ether or benzene.
The reaction proceeds at room temperature and is catalyzed by a strong acid catalyst such as sulfuric acid.

c.
Wolff-Kishner reduction: The resulting mixture is then treated with a solution of potassium hydroxide in water, which reduces thealkylation product to an alcohol.

d.
Wurtz-Fittig dehalogenation: The alcohol is then treated with a solution of sodium in a solvent such as ether or benzene, which dehalogenates the compound and forms the final product, 29-Nordammara-17(20),24-dien-21-oic acid.

2.
Synthesis of 16-(acetyloxy)-3,11-dihydroxy-(3α,4α,8α,9β,11α,13α,14β,16β,17Z)-compound with 2,2′-iminobis[ethanol] (1:1)
The synthesis of 16-(acetyloxy)-3,11-dihydroxy-(3α,4α,8α,9β,11α,13α,14β,16β,17Z)-compound with 2,2′-iminobis[ethanol] (1:1) involves several chemical reactions, including the reaction between 29-Nordammara-17(20),24-dien-21-oic acid and 2,2′-iminobis[ethanol] (1:1).
The synthesis process involves the following steps:

a.
Mixing of 29-Nordammara-17(20),24-dien-21-oic acid and 2,2′-iminobis[ethanol] (1:1)

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