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    Home > Medical News > Medical World News > The Production Process of 1-Boc-4-(4-methoxycarbonylphenyl)piperazine

    The Production Process of 1-Boc-4-(4-methoxycarbonylphenyl)piperazine

    • Last Update: 2023-05-16
    • Source: Internet
    • Author: User
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    The production process of 1-Boc-4-(4-methoxycarbonylphenyl)piperazine, also known as 4-Methoxycarbonyl-1,2-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-one, is a complex process that involves several steps and requires a high level of expertise and equipment.
    In the chemical industry, the production of this compound is typically carried out by specialized companies that have the necessary infrastructure and personnel to handle the process.


    The production process of 1-Boc-4-(4-methoxycarbonylphenyl)piperazine can be broken down into the following steps:


    1. Synthesis of the starting materials: The first step in the production process is the synthesis of the starting materials required for the production of 1-Boc-4-(4-methoxycarbonylphenyl)piperazine.
      These starting materials are typically synthesized through a series of chemical reactions using precursors such as amines, carboxylic acids, and other chemicals.
    2. Protection of the N-Boc Amine: The next step is the protection of the N-Boc amine, which is a crucial step in the production process.
      This step involves the use of protecting groups to prevent the amine from undergoing further reactions that could lead to unwanted side products.
    3. Coupling Reaction: The next step is the coupling reaction, which involves the reaction of the N-Boc amine with the 4-methoxycarbonylphenyl piperazine.
      This reaction typically involves the use of a coupling agent, such as dcc, HBTU, or EDCI, and is carried out in the presence of a solvent, such as DMF or THF.
    4. Deprotection of the N-Boc Amine: After the coupling reaction is complete, the N-Boc amine must be deprotected to reveal the final product.
      This step is typically carried out using a deprotecting agent, such as TFA or HCl, in the presence of a solvent, such as dichloromethane or ethyl acetate.
    5. Purification: The final product is typically purified using a variety of techniques, such as crystallization, chromatography, or distillation.
      This step is crucial to remove any impurities that may have been generated during the production process.

    In conclusion, the production process of 1-Boc-4-(4-methoxycarbonylphenyl)piperazine is a complex process that requires a high level of expertise and equipment.
    The process involves several steps, including the synthesis of starting materials, protection of the N-Boc amine, coupling reaction, deprotection of the N-Boc amine, and purification.
    Specialized companies in the chemical industry typically carry out this process, and they have the necessary infrastructure and personnel to handle the process effectively.


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