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, published last week, showed that patients with high blood pressure combined with three antihypertensive drugs can improve the effectiveness of treatment, but also to ensure safety. The study promises to change the way anti-depressants are given.
the new administration method uses three drugs, temisatan, ammonia chlordecone and ketamine, each at a lower dose than usual and placed in a capsule. Conventional therapy usually starts with a small dose of a single drug and considers increasing the dose or giving a new drug based on blood pressure control.
An international team of researchers from Australia, Sri Lanka and other countries reported that 700 patients with hypertension were recruited from 11 hospitals and clinics in Sri Lanka, who were randomly divided into two groups, with about half taking triple therapy and taking one capsule a day containing 20 milligrams of timishatan and 2. 5 mg of ammonia chlorpyrine and 12. 5 mg of ketamine, the other half using conventional therapy.
clinical trials showed that six months later, 70 percent of patients with triple therapy achieved their blood pressure control goals, compared with 55 percent of patients with conventional therapy.
in the proportion of side effects such as muscle pain, joint pain, dizziness, patients with triple therapy were similar to those with conventional therapy, and there was no significant difference between the two groups of patients who stopped taking drugs because of side effects.Ruth Webster of the University of New South Wales in Australia, one of the authors of the
paper, says it is time-and-effort to constantly review patients with high blood pressure to adjust medications and dosages, and many doctors and patients are afraid of trouble and do not follow the rules. Compared with conventional therapy, the method of triple drug use is simpler and more effective. (Source: Xinhua News Agency Zhou Zhou)