The new method reactivates genes that "suppress" tumors
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Last Update: 2020-12-28
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Source: Internet
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Author: User
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genes that "suppress" tumours tend to be "shut down" by cancer cells, and new methods can reactivate them to fight them, according to a study published today by University College London.
that some genes can stop tumors from growing when they are active, but cancer cells often use a protein called PRC2 to suppress the effects of these genes and "turn them off."
researchers at University College London and others, published in the British journal Nature-Structural and Molecular Biology, said they found that if the protein PRC2 was "bound" with ICS, it would not be able to "turn off" the genes.In the
experiment, the researchers first cultured cells of tumor tissue, where the role of the gene was inhibited by the protein PRC2, but after using technology to "bind" ICS to the protein, the protein left the gene, which reactivates the ability of the gene to suppress cancer cells.
, of University College London, said the next step would be to test what types of cancer this method could be used to develop new cancer treatments. (Source: Xinhua News Agency, Zhang Jiawei)
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