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The main effect and role of pharmaceutical grade methylparaben is to approve methylparaben, also known as methyl parahydroxybenzoate, also known as methylparaben or methylparaben, is an organic substance, chemical formula C8H8O3, white crystalline powder or colorless crystal, with soluble alcohol, ether and acetone, very slightly soluble in water properties, boiling point 270-280 °C
.
It is mainly used as a bactericidal preservative for organic synthesis, food, cosmetics and medicine, and is also used as a feed preservative
.
Because it has a phenolic hydroxyl structure, its antibacterial properties are stronger
than that of benzoic acid and sorbic acid.
Its mechanism of action is: to destroy the cell membrane of microorganisms, denature proteins in cells, and inhibit the activity of respiratory enzyme lines and electron delivery
enzyme lines of microbial cells.
Cosmetic preservatives
.
It is a phenolic preservative, which is effective against various molds, yeasts and bacteria, but the bactericidal power of paraben is low, and it is usually mixed with paraben ethyl ester, which has good addition and synergy
.
The amount of addition is 0.
1% to 1.
0%.
Antiseptic activity is related to the pH of the solution, when the pH value is 7, its activity is 2/3 of the original activity; if the pH value is 8.
5, it is reduced to half
of the original activity.
It will be bound by some polymer compounds such as methylcellulose, gelatin proteins, etc.
and make it lose its antiseptic activity
.
It is used as an antiseptic fungicide in the pharmaceutical industry, and is also used in organic synthesis and preservative additives for food, spices
, film, etc.
Similar products produced by similar production methods, p-hydroxybenzene (parabens, propyl parahydroxybenzoate) and propyl parahydroxybenzoate (paraben propyl), are also disinfectant preservatives
.
The product is irritating to the
skin.