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6-fluoroH-iMidazo[1,2-a]pyridin-3-carboxylic acid, commonly referred to as H-iMidazo[1,2-a]pyridin-3-carboxylic acid 6-fluoro-2,3-dihydro-1H-imidazo[1,2-d][1,4]benzoxazepin-9-one, is an important intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other chemical products.
This organic compound is composed of a benzoxazepine ring system, which is a well-known scaffold in medicinal chemistry, and a unique fluorine substituent at the 6-position of the pyridine ring.
H-iMidazo[1,2-a]pyridin-3-carboxylic acid 6-fluoro-2,3-dihydro-1H-imidazo[1,2-d][1,4]benzoxazepin-9-one is synthesized through a multi-step process that involves the synthesis of the basic structure of the molecule, followed by the introduction of the fluorine substituent and the final transformation into the desired product.
The synthesis of this compound requires a high level of expertise and knowledge in organic chemistry, as well as access to specialized equipment and reagents.
The synthesis of H-iMidazo[1,2-a]pyridin-3-carboxylic acid 6-fluoro-2,3-dihydro-1H-imidazo[1,2-d][1,4]benzoxazepin-9-one typically involves the following steps:
- Synthesis of the basic structure: The synthesis of the basic structure of the molecule, which includes the pyridine ring and the benzoxazepine ring, is typically achieved through a sequence of reactions involving the reaction of a suitable starting material, such as a pyridine or aniline, with a reactive intermediate, such as an aldehyde or a ketone.
- Introduction of the fluorine substituent: The introduction of the fluorine substituent at the 6-position of the pyridine ring is typically achieved through a sequence of reactions involving the reaction of a fluorine-containing reagent, such as fluorosulfonic acid or a fluorinating reagent, with the basic structure of the molecule.
- Final transformation: The final transformation of the molecule into the desired product is typically achieved through a sequence of reactions, such as hydrolysis, oxidation, or reduction, depending on the specific properties of the molecule.
The synthesis of H-iMidazo[1,2-a]pyridin-3-carboxylic acid 6-fluoro-2,3-dihydro-1H-imidazo[1,2-d][1,4]benzoxazepin-9-one requires the use of specialized equipment and reagents, as well as a high level of expertise and knowledge in organic chemistry.
The synthesis of this compound is typically carried out in a dedicated synthesis laboratory by trained chemists, and the entire process can take several steps and several hours to complete.
The use of H-iMidazo[1,2-a]pyridin-3-carboxylic acid 6-fluoro-2,3-dihydro-1H-imidazo[1,2-d][1,4]benzoxazepin-9-one in the synthesis of pharmaceuticals, agrochemicals, and other chemical products is due to its unique properties, including its ability to act as a potent and selective antagon