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The 6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-cyclopropyl-amine is a chemical compound that is widely used in the pharmaceutical and chemical industries.
It is known for its unique properties, which make it highly effective in various applications.
In this article, we will explore the instruction of 6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-cyclopropyl-amine, its production process, and its applications in the chemical industry.
Introduction to 6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-cyclopropyl-amine
6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-cyclopropyl-amine, also known as MK-8628, is a synthetic compound that belongs to a class of drugs known as PI3Kδ inhibitors.
PI3Kδ is an enzyme that plays a crucial role in signal transduction, cell proliferation, and inflammation.
Inhibition of PI3Kδ has been shown to have potential therapeutic effects in various diseases, including cancer, inflammation, and autoimmune disorders.
Production of 6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-cyclopropyl-amine
The production of 6-Chloro-2-methanesulfonyl-pyrimidin-4-yl)-cyclopropyl-amine involves several chemical reactions, including nitration, halogenation, and Suzuki coupling.
The process can be summarized as follows:
- Nitration of 2-cyanopyrimidine: 2-Cy
