The Instruction of 5-METHOXY-PYRIDIN-2-YLAMINE

The 5-methoxy-pyridine-2-ylamine is a chemical compound that is commonly used in the pharmaceutical and chemical industries.
This compound is used as an intermediate in the production of various medicines and other chemical products.
In this article, we will discuss the instruction of 5-methoxy-pyridine-2-ylamine, including its properties, uses, production, and safety measures.

Properties of 5-methoxy-pyridine-2-ylamine

5-methoxy-pyridine-2-ylamine is a white or almost white, odorless, crystalline powder.
It is slightly soluble in water and highly soluble in organic solvents.
The molecular formula of this compound is C6H9NO2 × HCl.
Its molar mass is 157.
64 g/mol.
The chemical structure of 5-methoxy-pyridine-2-ylamine is shown below:

[C6H9NO2]Cl

Uses of 5-methoxy-pyridine-2-ylamine

5-methoxy-pyridine-2-ylamine is used as an intermediate in the production of various medicines and other chemical products.
It is used in the production of anti-inflammatory drugs, antiepileptic drugs, and antibiotics.
It is also used as a research chemical in various laboratory experiments.

Production of 5-methoxy-pyridine-2-ylamine

5-methoxy-pyridine-2-ylamine is produced by various chemical methods.
One of the most common methods is the reaction of 2-methoxy-5-nitroaniline with sodium hydride in the presence of a solvent such as DMF.
The reaction produces 5-methoxy-pyridine-2-ylamine hydrochloride, which is then purified and crystallized to yield the final product.
The chemical equation for this reaction is shown below:

2-methoxy-5-nitroaniline + 2 NaH → 5-methoxy-pyridine-2-ylamine + 2 NaNO2 + H2O

Another method for the production of 5-methoxy-pyridine-2-ylamine involves the reaction of 2,5-dimethoxybenzaldehyde with ammonia in the presence of a solvent such as DMF.
The reaction produces 5-methoxy-pyridine-2-ylamine hydrochloride, which is then purified and crystallized to yield the final product.
The chemical equation for this reaction is shown below:

2,5-dimethoxybenzaldehyde + 4 NaOH + 4 H2O → 5-methoxy-pyridine-2-ylamine + 4 Na2CO3 + 4 NH3

Safety measures for 5-methoxy-pyridine-2-ylamine

5-methoxy-pyridine-2-ylamine is a toxic chemical that should be handled with caution.
It is highly soluble in water and can cause irritation to the eyes, skin, and respiratory system.
It is also known to cause cancer in humans.
Therefore, it is important to take the necessary safety measures when handling this chemical.
Some of the safety measures that should be taken include wearing protective clothing, including gloves and goggles, and working in a well-ventilated area.
It is also important to avoid ingesting this chemical and to wash hands thoroughly after handling.

Conclusion

5-methoxy-pyridine-2-ylamine is a