The Instruction of [3-[2-(3-Chlorophenyl)ethyl]-2-pyridinyl](1-methyl-4-piperidinyl)methanone hydrochloride

Instruction of 3-[2-(3-Chlorophenyl)ethyl]-2-pyridinylmethanone hydrochloride is a commonly used compound in the chemical industry.
It is also known as MEPHISONE HCl, and it is used as an intermediate in the synthesis of certain pharmaceuticals, agrochemicals, and other chemical products.

3-[2-(3-Chlorophenyl)ethyl]-2-pyridinylmethanone hydrochloride is a white to off-white powder with a slightly bitter taste.
It is soluble in water, methanol, and ethanol, but it is insoluble in ether and hexane.
The molecular formula for this compound is C21H26ClNO•HCl, and its molecular weight is 376.
90 g/mol.

This compound is classified as a phenylpyridine derivative, which is a type of organic compound that contains a five-membered ring with a nitrogen atom in the center and a phenyl group attached to it.
Phenylpyridine derivatives are commonly used in the synthesis of pharmaceuticals and other chemical products due to their unique physiochemical properties.

3-[2-(3-Chlorophenyl)ethyl]-2-pyridinylmethanone hydrochloride is synthesized by a multi-step reaction process that involves several chemical reactions such as halogenation, alkylation, and hydrolysis.
The starting materials used in the synthesis of this compound are (2-chloroethyl)-2-pyridine, 1-methyl-4-piperidine, and HCl.

The synthesis of 3-[2-(3-Chlorophenyl)ethyl]-2-pyridinylmethanone hydrochloride involves several steps, including the following:

1. Halogenation: In this step, (2-chloroethyl)-2-pyridine is treated with a halogen molecule such as chlorine to form 2-chloro-[3-(2-chloroethyl)-2-pyridine]-1,4-benzenedicarboxylate.
   
2. Alkylation: In this step, the compound obtained from the halogenation step is treated with 1-methyl-4-piperidine in the presence of a strong acid catalyst to form [3-(2-chloroethyl)-2-pyridine]-1,4-diyl diazide.
   
3. Hydrolysis: In this step, the diazide obtained from the alkylation step is treated with water to form [3-(2-chloroethyl)-2-pyridine]-1,4-diyl hydrazide.
   
4. Hydrolysis and decarboxylation: In this step, the hydrazide obtained from the hydrolysis step is treated with a strong acid such as HCl to form [3-(2-chloroethyl)-2-pyridyl]-1,4-piperazine-1,4-dicarboxylate.
   
5. Hydrochloride salt formation: In this step, the carboxylic acid obtained from the hydrolysis and decarboxylation step is treated with HCl to form 3-[2-(3-chlorophenyl)ethyl]-2-pyridinylmethanone hydroch