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2H-Pyrrolo[3,2-c]pyridin-2-one, also known as 2-hydroxy-3,2-pyridinone or 2HPP, is a versatile chemical compound that is widely used in the pharmaceutical, agrochemical, and chemical industries.
It is a white to off-white solid that is soluble in water and many organic solvents.
2HPP is synthesized through several different methods, but the most commonly used method involves the hydrolysis of 2-chloromethyl-1,3-oxazepine.
One of the most important applications of 2HPP is in the manufacture of pharmaceuticals.
It is a key intermediate in the synthesis of several drugs, including the antiallergic medication Zyrtec (cetirizine) and the antiviral medication Tamiflu (oseltamivir).
2HPP is also used in the production of other pharmaceuticals such as antibiotics and anti-cancer drugs.
In addition to its use in pharmaceuticals, 2HPP is also used in agrochemicals.
It is a precursor to several herbicides, including atrazine and propazine.
Atrazine is one of the most widely used herbicides in the world, and is used to control weeds in crops such as corn, sorghum, and sugar cane.
Propazine is also widely used, particularly in turf and ornamental applications.
Another important application of 2HPP is in the production of polymers.
It is a monomer used in the production of polyamides, which are used in a variety of applications, including textiles, packaging, and engineering plastics.
2HPP is also used in the production of polyurethanes, which are used in applications such as foam insulation, automotive parts, and furniture.
2HPP is also used in the production of dyes and pigments.
It is used as a substrate in the production of pigments for use in the printing ink and paint industries.
2HPP is also used in the production of dyes for use in textile and leather industries.
In the chemical industry, 2HPP is used as a building block for the synthesis of other chemicals.
It is converted into other compounds such as substituted 1,3-oxazepines, which are used in the production of pharmaceutical and agrochemical intermediates.
Overall, 2H-Pyrrolo[3,2-c]pyridin-2-one,1,3-dihydro-(9CI) is a versatile building block in the chemical industry, it is widely used in various applications such as pharmaceuticals, agrochemicals, polymers, dyes and pigments, and its derivatives have a wide range of applications.
However, it is important to be aware of the potential risks associated with handling and using 2HPP, including the potential for fire or explosion, and proper safety measures should be taken to avoid accidents.
It is important to note that the safety precautions and regulations for handling 2HPP may vary depending on the country and region where the product will be used.
Therefore, it is necessary to check the regulations and recommendations of the regional chemical authorities before handling the product.