The Instruction of 1-Imidazo[1,2-b]pyridazin-3-ylethanone

The Instruction of 1-Imidazo[1,2-b]pyridazin-3-ylethanone: A Comprehensive Overview for the Chemical Industry

1-Imidazo[1,2-b]pyridazin-3-ylethanone, commonly abbreviated as 1-IMY, is a synthetic chemical compound that has been widely used in various industrial applications.
Due to its unique structure and properties, it has attracted significant attention from researchers and industrialists alike.
In this article, we will provide a comprehensive overview of 1-IMY, including its properties, synthesis, applications, safety measures, and regulatory considerations.

Structure and Properties of 1-Imidazo[1,2-b]pyridazin-3-ylethanone

1-IMY is a colorless to yellowish liquid with a characteristic odor.
It is soluble in most organic solvents, such as ethanol, methanol, and acetonitrile, but insoluble in water.
The molecular formula for 1-IMY is C10H7N3 with a molecular weight of 137.
17 g/mol.

The chemical structure of 1-IMY consists of a five-membered imidazole ring fused to a pyridine ring.
The imidazole ring contains a nitrogen atom, which is part of a secondary amine group, while the pyridine ring has a nitrogen atom in the ortho position to a methylene group.
The ethyl group on the nitrogen atom makes 1-IMY a functionalized imidazo[1,2-b]pyridine.

Synthesis of 1-Imidazo[1,2-b]pyridazin-3-ylethanone

1-IMY can be synthesized using various methods.
The most common method involves the reaction of 2-cyanopyridine with sodium hydroxide followed by treatment with β-alanine.
This reaction forms an imidazolate salt, which is then transformed into 1-IMY by treating with sodium hydroxide and then hydrogenation.

Another method for the synthesis of 1-IMY involves the reaction of N-iodosuccinimide with sodium hydride in the presence of 1,2-dichloroethane.
The resulting intermediate is then treated with sodium hydroxide and hydrogenated to obtain 1-IMY.

Applications of 1-Imidazo[1,2-b]pyridazin-3-ylethanone

1-IMY has a wide range of applications in the chemical industry due to its unique properties.
Some of its most common applications include:

• As a building block for the synthesis of dyes, pigments, and other colorants
• As a chemical intermediate for the production of pharmaceuticals and agrochemicals
• As an additive in plastics, coatings, and other polymer products
• As a solvent for various organic compounds

Safety Measures for Handling 1-Imidazo[1,2-b]pyridazin-3-ylethanone

1-IMY is a moderately toxic chemical compound and should be handled with caution.
It can cause skin irritation, respiratory problems, and other health issues if proper safety measures are not followed.
The handling of 1-IMY should be done in a well-ventilated area, and protective clothing, such as gloves and goggles, should be worn.

In case of skin contact, the affected area should be washed immediately with plenty of water.
If 1-IMY is ingested, seek medical attention immediately.
It is also recommended to store 1-IMY in a cool, dry place and to dispose of it properly