The Instruction of 1-(6-Chloro-pyridazino-3-yl)piperidine

In the chemical industry, one of the most important aspects is the efficient and safe production of chemical compounds.
One such compound is 1-(6-chloro-pyridazino-3-yl)piperidine, which is commonly used as a pharmaceutical intermediate and research chemical.
In this article, we will discuss the instruction of 1-(6-chloro-pyridazino-3-yl)piperidine, which is essential for its safe and efficient production in the chemical industry.

Introduction:

1-(6-Chloro-pyridazino-3-yl)piperidine is a synthetic compound that is commonly used in the pharmaceutical industry as a research chemical and intermediate.
It is also used as a ligand in coordination chemistry.
In order to safely and efficiently produce this compound, it is important to follow the instructions closely.

Preparation of Starting Materials:

The synthesis of 1-(6-chloro-pyridazino-3-yl)piperidine typically starts with the preparation of several starting materials.
These materials must be of high purity and must be handled with care to avoid contamination.
The following are the typical starting materials used in the synthesis of 1-(6-chloro-pyridazino-3-yl)piperidine:

• 2-Chloropyridine
• 1,4-Dioxane
• Benzaldehyde
• Palladium(II) acetate
• Triphenylphosphine

Synthesis of 1-(6-Chloro-pyridazino-3-yl)piperidine:

The synthesis of 1-(6-chloro-pyridazino-3-yl)piperidine typically involves several steps.
The following is a typical synthesis procedure:

1. In a round-bottomed flask equipped with a magnetic stirrer, add 2-chloropyridine (2 g, 15 mmol) and 1,4-dioxane (20 mL)