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The Food and Medicine Homologous Functional Food Team of Yunnan Agricultural University: α-linolenic acid promotes the proliferation of mouse intestinal stem cells by regulating the intestinal flora

 Last Update: 2022-01-07
 Source: Internet
 Author: User

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Recently, the team of Professor Sheng Jun and Professor Tian Yang of Yunnan Agricultural University published an online cover paper "Short-chain fatty acids produced by Ruminococcaceae mediates α -Linolenic acid promote intestinal stem " in the international authoritative journal Molecular Nutrition & Food Research (IF=5.

Intestinal epithelium is the fastest renewal tissue in adult mammals, and it plays an important role in nutrient absorption, hormone release, and immune barrier function

Intestinal microbes play a key role in regulating the homeostasis and integrity of the intestine, and shaping the various morphological and functional characteristics of different intestinal regions and different intestinal cell subgroups

The study found that ALA promotes the proliferation of ISCs by activating the Wnt/ β- catenin signaling pathway, which in turn promotes the growth of the small intestine and villi of mice

Sheng Jun, PhD, Professor, PhD supervisor

Tian Yang, PhD, Professor, PhD supervisor

The article, author's introduction and pictures are from the Food and Medicine Homologous Functional Food Team of Yunnan Agricultural University.

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