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Widespread stage small cell lung cancer (extensive-stage cell lung cancer, ES-SCLC) accounts for about two-thirds of small cell lung cancer (small cell lung, SCLC), treatment mainly chemotherapy, auxiliary radiotherapy and other comprehensive treatment.
ES-SCLC is a highly invasive, rapidly deteriorating form of lung cancer that, although initially responded to chemotherapy, usually relapses, highlighting the urgent need for new treatments.
recently, AstraZeneca's Durvalumab has been approved by the European Union to treat adult patients with ES-SCLC with a variety of chemotherapy drugs.
in CASPIAN PHASE III clinical trials, Imfinzi combined chemotherapy first-line therapy showed significant overall lifetime (OS) benefits (13.0 months vs. 10.3 months) and an increase in objective remission rates (68 percent vs. 58 percent) compared to chemotherapy alone.
The first immunotherapy in patients with widespread small cell lung cancer that improves both survival and response rates," said Dave Fredrickson, executive vice president of Oncology at AstraZeneca.
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