The effect of bilberry extract on the contrast sensitivity of patients with non proliferative diabetic retinopathy

Recently, researchers from Shengjing Hospital Affiliated to China Medical University published a paper to observe the therapeutic effect and contrast sensitivity (CS) change of blueberry extract (VME) in the treatment of non proliferative diabetic retinopathy (NPDR) VME can improve CS of NPDR patients and protect diabetic retina This article was published in the 01 issue of new progress in ophthalmology in 2014 75 patients with mild to moderate NPDR were randomly divided into two groups, 42 eyes in the experimental group and 33 eyes in the control group The experimental group was given VME 200 mg, three times a day, orally; the control group was given placebo vitamin C tablets, 100 mg, three times a day, orally; the course of treatment was 8 weeks The best corrected visual acuity (BCVA) was examined before and after treatment, and the CS was examined in the mode of 6C · D-1 and 12C · D-1 A total of 69 patients (38 eyes in the experimental group and 31 eyes in the control group) with mild to moderate NPDR completed the clinical observation for 8 weeks There was no significant difference between the two groups in general conditions, gender, age, fasting blood glucose, glycosylated hemoglobin and other indicators (P > 0.05); there was no statistical difference between the two groups (t = 0.189, P = 0.239); after treatment, the BCVA value of the test group was 0.220, 0.012 higher than before treatment, but there was no statistical difference (t = 1.273, P = 0.211) The average CS of the patients in the experimental group in the medium and high frequency mode (6c · D-1 and 12C · D-1) was 85.656 and 47.281, respectively Compared with the control group, the difference was not statistically significant (P < 0.05) After treatment with VME, the CS value of the experimental group was significantly higher than that before treatment (89.313 and 50.941, respectively), the difference was statistically significant (P < 0.001); compared with the control group, the difference was statistically significant (t = 7.538 and 11.868, both P < 0.001).