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The CREB binding protein (CBP)/β-catenin inhibitor E7386 jointly developed by Eisai and PRISM BioLab achieved clinical POC (proof of concept)

 Last Update: 2021-12-02
 Source: Internet
 Author: User

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Tokyo, November 12, 2021/PRNewswire/ - Eisai Co.

Eisai is conducting a phase I clinical study of E7386 monotherapy for solid tumors and a phase Ib clinical trial of E7386 combined with lenvatinib mesylate (product name: LENVIMA®, "lenvatinib").

Based on the results of the POC, Eisai initiated a phase Ib/II clinical trial of E7386 combined with anti-PD-1 therapy pembrolizumab in the treatment of solid tumors (Study 201) in Japan

Dr.

Dai Takehara, President and CEO of PRISM, said: "The results of E7386's clinical POC show that PRISM's drug discovery platform is an effective choice for new drug targets that are considered difficult

Source: Eisai China

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