The clinical trial results of compound artemisinin piperaquine tablets (yuetekuai) of Chinese pharmaceutical companies in Comoros were good

Malaria has been endemic for a long time in Comoros, a poor island country on the east coast of Africa This disease can lead to high fever, systemic pain, and very few deaths from cerebral malaria This month, a Chinese company (New South Artemisia science and Technology Co., Ltd.) successfully conducted an unusual experiment with a new drug - compound artemisinin piperaquine tablets (yuetekuai) By applying the drug to the national population of the Comoros, the manufacturer of the drug proved its effectiveness Previously, no one has tried to end malaria infection in a specific population through continuous and closed medication According to the report, artemisinin is the main component of yuetekuai, which is a traditional Chinese medicine and an important drug for malaria treatment in the past decade In the Comoros trial, yuetekuai was used in combination with a low dose of primaquine Primaquine is also a drug for malaria, but it has a lot of side effects In the three-month experiment, the whole population of Comoros took yuetekuai three times at the same time, which quickly made the mosquitoes lose the human host, thus preventing the spread of malaria Three months is the cycle in which mosquitoes transmit Plasmodium falciparum from one person to another Once there is no human host, malaria can no longer spread and the disease disappears from the Comoros The report said that this situation seems to have been realized now, as predicted by Chinese scientists If the Comoros does eliminate malaria, it should soon replace the traditional anti malarial approach of spraying insecticides at home and on mosquito nets to kill mosquitoes, while providing preventive drugs to stop malaria parasites A professor of traditional Chinese medicine in Guangzhou said it was more effective to "kill Plasmodium in human body" than to kill every mosquito "We changed our minds." He said The Comorian government says the successful trial in China has saved the country $11 million a year in medical costs, not to mention the productivity that the health of the entire population brings back However, Guangdong Express has not yet been tested or approved by who or tropical medicine experts, the report said The toxicity and side effects of the drug, produced by Guangdong New South Artemisia science and Technology Co., Ltd., are unclear In addition to the potential risks, scientists need to determine what the consequences will be in the event of a resurgence of malaria in a population that has no immunity or is resistant to artemisinin once the spread of malaria has been eliminated If the comorians don't have malaria or harmful side effects in the coming summer in the southern hemisphere, the Chinese treatment will prove its value, the report said In that way, the experiment could be carried out elsewhere, and malaria could become another terrible disease to be eradicated Since 2007, Guangzhou University of traditional Chinese medicine has achieved remarkable results in the high malaria area of moeli island and Anjouan island of Comoros by adopting the "yuetekuai" mass prevention and treatment, national drug taking program to eliminate infectious sources and eliminate malaria Tens of thousands of Comorian people have benefited from this project, which has been highly praised by the Comorian people The international community has paid close attention to this project After the arrival of the antimalarial drugs in Comoros, the third phase of the malaria eradication plan in Comoros will be implemented, so that the people of Comoros can quickly get rid of malaria hazards Professor Song Jianping, deputy director of Artemisia annua research center of Guangzhou University of traditional Chinese medicine, said at the promotion meeting that "Guangdong express" is the concrete embodiment of China's new anti malaria concept Professor Song believes that in terms of malaria eradication, it is more effective to cut off the reproduction of Plasmodium in human body than to focus on mosquito control He said that "yuetekuai", as the latest generation of artemisinin compound antimalarial drug, can only be taken twice within 24 hours It not only shortens the course of treatment, but also saves costs, and has less side effects It is very suitable for promotion in Africa In fact, the drug has been marketed on a small island in the Comoros, an Eastern African country, since 2007, resulting in a reduction in the malaria carrying rate of local people from 22% to less than 2% within 11 months.