The child, male, 7 years old, was born with a history of asphyxiation.

Neurology"Basic Information"children, male, 7 years old"Main complaint"history of asphyxia at birththe two-sided ventricle, radiation crown sedative abnormal signal, T1WI slightly Low signal, T2WI is slightly higher signal, FLAIR is a higher signal, the volume of brain white matter is reduced to the side ventricle triangle distribution, adjacent to the brain back tends to white matter, the edge of the double side ventricle is irregular, the wave-like changeThe body is thinnerClinical DiagnosticsWhite matter softening around the lateral ventricle"case summary"lateral ventricle leukomalacia (PVL) is a late change in ischemic hypoxic encephalopathy and is the main cause of cerebral palsy (primarily spasmous lower or quadriplegic palsy), PVL is a secondary cerebral white matter disease, seen in children who are born to suffocationIt is now generally believed that PVL is related to ischemia, hypoxia and infection, PVL mainly damages shaft ropes and less protrusive glial cells, but the pathogenesis is not yet clearPVL is good in premature babies, the reason may be related to different brain damage mechanisms at different stages of development, early and mid-pregnancy brain abnormalities are mostly developmental malformations, and late (after 3 months) mostly cerebrovascular changesBlood supply around the ventricle comes from the end artery of the ventricle and far ventricle region respectively, the late branch circulation of the immature end-of-life arterial deep branch has not been established, the late stage of pregnancy is sensitive to ischemic hypoxia, the cortex is only affected when the lesions are widespread, so PVL is more common in premature babiesLate to the end of pregnancy, the side branch circulation has been established, the sensitive area changed to the cortex and subcutaneous white matter and base section area, full-term ischemia, hypoxic brain injury is mostly found in the above-mentioned partsPVL can lead to cerebral palsy (mainly convulsive double lower limb palsy, quadriplegic palsy), intelligence backwardness, convulsions, as well as a variety of eye abnormalities, such as eye shock, squint, vision loss, and so on, its clinical symptoms are closely related to CT, MRI changes CT performance is: side ventricle body and triangular part expansion, irregular shape; The white matter of the brain around the triangular and body parts was significantly reduced, and the white matter in the center of the semi-egg circle of the heavy man was also significantly reduced; The trench, the crack widening deepening, the hypothalamus of the gray matter directly close to the wall of the ventricle, in which there are few white matter components MRI is more sensitive than CT, mainly as follows: (1) brain white matter signal change: white matter T2WI high signal around the ventricle; (2) Reduction of brain white matter: the triangular and body around the brain white matter significantly reduced, the weight of the semi-egg circle center of the white matter is also significantly reduced; (3) Side ventricle changes: the side ventricle body and triangular part of the expansion, irregular appearance; (4) Brain trench, brain fissure change: the brain trench, the crack widening deepening (5) the body change, mainly for the abnormal development of the body source: