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People with digestive problems are at higher
Alzheimer's disease is the most common type of dementia that deprives people of their memory and ability to
The ECU's Center for Precision Health recently confirmed the genetic link between AD and several intestinal disorders, deepening our understanding of
Lead researcher Emmanuel Adewuyi, Ph.
"This study provides new insights into the genetics behind the observed simultaneous occurrence of Alzheimer's disease and intestinal disease," said
Professor Simon Rouse, director of the Centre for Precision Health and head of research, said that while the study did not conclude that intestinal diseases or intestinal disorders cause AD, the findings were very valuable
Professor Adewuyi said: "These findings provide further evidence for the concept of the 'gut-brain' axis, which is a bidirectional connection
Is cholesterol key?
When the researchers analyzed the shared gene further, they found other important links between AD and gut diseases — such as the role
Dr.
Hope for the future
In future AD treatments, the association of cholesterol may prove crucial
Although there is no known treatment, the findings suggest that cholesterol-lowering drugs (statins) are effective
"Evidence suggests that statins have properties that help reduce inflammation, regulate immunity, and protect the gut," said
However, he said more research is needed and patients need to be individually evaluated to determine whether they would benefit
References:
A large-scale genome-wide cross-trait analysis reveals shared genetic architecture between Alzheimer’s disease and gastrointestinal tract disorders