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    Home > Biochemistry News > Biotechnology News > The biochemical "switch" that controls the development of regulatory T cells found

    The biochemical "switch" that controls the development of regulatory T cells found

    • Last Update: 2022-01-08
    • Source: Internet
    • Author: User
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    According to a report on the 29th by the physicist organization network, immunologists from the St.


    Regulatory T cells are a subgroup of mature T cells with regulatory functions, which can suppress immune responses and help maintain and fine-tune immune balance


    In the latest study, the researchers focused on the Foxp3 protein.


    The researchers discovered a biochemical process consisting of three steps in mouse T cells: first, precursor cells receive guidance signals and initiate the development of regulatory T cells; then, a table called histone acetylation The genetic mechanism acts as a switch to turn on the expression of Foxp3, just like a battery starts an engine


    Researchers have previously reported that vitamin C and short-chain fatty acid butyrate produced by healthy bacteria in the intestine can enhance the expression of Foxp3.


    Dr.


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