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5-Pyridin-2-ylthiophene-2-carbaldehyde, also known as C-5 ring-opened pyridoxal-5-phosphate (C5-OP), is an important intermediate in the chemical industry, with a wide range of applications in various fields.
- Pharmaceuticals: C5-OP is used as an intermediate in the production of certain pharmaceuticals, such as antihistamines, antidepressants, and antipsychotics.
It is also used in the synthesis of certain antibiotics, such as tetracyclines and chloramphenicol. - Agrochemicals: C5-OP is used as an intermediate in the production of pesticides, herbicides, and fungicides.
It is also used in the synthesis of certain plant growth regulators. - Materials: C5-OP is used in the production of certain polymers and plastics, such as polyesters and polyurethanes.
It is also used as a building block in the synthesis of certain conducting polymers. - Cosmetics: C5-OP is used in the production of certain cosmetics and personal care products, such as shampoos and conditioners.
- Printing Ink: C5-OP is used in the production of printing inks, especially for offset printing.
- Photoinitiators: C5-OP is used as a photoinitiator in the production of certain photopolymerization systems, such as UV curable inks, adhesives, and coatings.
- Food additives: C5-OP is used as a food additive, specifically as a flavoring agent in certain food products.
C5-OP is typically synthesized by a multi-step process that involves the reduction of 5-pyridin-2-ylthiophene-2-carbaldehyde (C5-CARB) to form C5-OP.
The reduction can be achieved using various reducing agents, such as lithium aluminum hydride (LiAlH4) or diisobutylaluminum hydride (DIBAH).
One of the most significant advantages of C5-OP is its versatility as an intermediate.
It can be used in the synthesis of a wide variety of chemicals, which makes it a valuable building block in the chemical industry.
Additionally, C5-OP is generally less expensive and easier to synthesize than many other building blocks, which makes it a cost-effective option for chemical synthesis.
In conclusion, 5-Pyridin-2-ylthiophene-2-carbaldehyde (C5-OP) is a versatile intermediate with a wide range of applications in the chemical industry, including pharmaceuticals, agrochemicals, materials, cosmetics, printing ink, photoinitiators, and food additives.
Its versatility, low cost, and ease of synthesis make it a valuable building block in the chemical industry.