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    Home > Biochemistry News > Biotechnology News > The anti-cancer magic weapon hidden in the desert may solve chemotherapy resistance

    The anti-cancer magic weapon hidden in the desert may solve chemotherapy resistance

    • Last Update: 2021-12-01
    • Source: Internet
    • Author: User
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    There are a special kind of plants in the dry deserts of Australia.


    This small plant that survives in extreme environments has not only become an easy-to-care horticultural plant due to its high drought resistance, it may even help us solve the number one problem in anti-cancer: the resistance of anti-cancer drugs


    Most deaths of cancer patients are related to drug resistance.


    At present, inhibiting the function of cancer cell drug efflux pump has become an important research direction to reduce drug resistance


    Professor Dan Stark of the University of Copenhagen tends to find new inspirations in traditional medicinal plants.


    He showed great interest in this.


    According to a study published in Biomolecules by Professor Stark and colleagues, they isolated a substance called flavonoids from these plants, which has the effect of inhibiting the efflux pump function


    When cancer cells develop resistance to this drug, many efflux pumps will be produced on their surface to expel the drug out of the cell.


    In addition to cancer cells, many drug-resistant bacteria also have a large number of efflux pumps on the surface, which can help them escape the pursuit of antibiotics


    Professor Stark said that he was not shocked by this result.


    Note: The original text has been deleted

    Reference materials:

    [1] Ancient natural medicine could improve cancer treatment.


    [2] Malene J.


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