-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
CompilationFan Dongdong
The CGRP patent dispute between Ajovy manufacturer Teva and Emgality developer Eli Lilly is heating up again
.
On Tuesday, after the US Patent and Trademark Office obtained two new Ajovy patents, Teva filed a new lawsuit against Eli Lilly in the Federal Court of Massachusetts in the United States
.
The Israeli drugmaker said that Eli Lilly’s migraine prevention drug Emgality infringed two of Ajovy’s newly obtained patents
.
The company is seeking to prevent Eli Lilly from manufacturing and selling its CGRP inhibitor drug Emgality in the United States and is seeking compensation
Teva and Eli Lilly followed Amgen into the CGRP migraine market in 2018
.
After Emgality was approved, Teva sued Eli Lilly for alleged infringement of 9 Ajovy patents
Eli Lilly challenged the patents held by these Teva Ajovy in the US Patent and Trademark Office, with mixed results
.
The agency announced the invalidation of 6 patents held by Ajovy in early 2020, but maintained the remaining 3 patents
As Teva CEO Kåre Schultz makes a major business transformation, the company has identified Ajovy as a key growth driver
.
The company hopes that its innovative drugs can save the company from the loss of sales caused by the sluggish US generic drug market and the loss of exclusive patents for the once best-selling multiple sclerosis drug Copaxone
Ajovy is a monoclonal antibody drug that targets the calcitonin-related gene peptide (CGRP) ligand and blocks its binding to the receptor
.
CGRP is a neuropeptide that has been shown to be released during migraine attacks and is considered to be the cause of migraine attacks
However, so far, Ajovy's performance is the weakest of the three anti-CGRP drugs
.
According to statistics from the Royal Bank of Canada Capital Markets on IQVIA data last week, Novartis and Amgen's Aimovig lead their peers with a market share of more than 40%
Schultz stated on a recent conference call that the company's goal is to eventually occupy one-third of the CGRP market in the next few years
.
Competition in the migraine market will intensify in 2021
Reference source: Teva, after locking up new Ajovy patents, sues Eli Lilly again in heated migraine drug fight