Taxol preparation plant will be put into production

Taxus, known as the "giant panda" in plants, is recognized as a rare and endangered natural anti-cancer plant in the world However, under natural conditions, the growth rate of Taxus chinensis is slow and its regeneration ability is poor The State Forestry Administration classified it as a first-class rare protected tree species The reporter learned that Wuxi Hongdou Group has mastered the rapid propagation technology of Taxus chinensis and solved the international problem of serious shortage of Taxus chinensis seedlings In September this year, paclitaxel preparation plant will also be put into production After completion, it can produce various specifications of anti-tumor drug injection and freeze-dried powder injection, with an annual output of 6 million pieces, which can meet the needs of 250000 cancer patients According to Zhou Yaoting, chairman of China yew Conservation Committee and chairman of the board of directors of Hongdou Group, Hongdou Group has been studying yew since 1997, and started large-scale cultivation of yew in Wuxi in 2001 In view of the slow growth and poor regeneration ability of Taxus, the rapid propagation technology of Taxus was successfully developed after 10 years Now cultivated "red bean brand" Taxus can grow 40-50 cm per year, and three-year seedlings can be cut off to extract taxol Due to the originality of rapid propagation technology and seed germination technology cultivation of Taxus, the technology is applied for a national invention patent, and "rapid propagation technology and industrialization of Taxus" is listed as the national Spark Program project Hongdou Group adopts advanced gap standard (quality management standard of Chinese herbal medicine production) to Plant Taxus mairei on a large scale; adopts enzyme-linked immunosorbent assay to detect taxol content and select Taxus mairei with high taxol content; adopts high-tech means to overcome the rapid propagation technology of Taxus mairei, so that it can be processed and utilized within 4 to 5 years, so as to solve the serious problem of Taxus mairei seedlings The shortage of taxol makes it possible to extract taxol in large quantities to make anticancer drugs! At present, Hongdou Group has built a Taxus ecological park of 30000 mu, and has cultivated 30 million Taxus annual and above, and more than 6 million Taxus seedlings annually, becoming the largest seedling breeding base of Taxus chinensis in China and one of the largest seedling cultivation bases of Taxus chinensis in the world The paclitaxel preparation plant will be put into operation to benefit cancer patients, said Zhou Yaoting Hongdou Group has also achieved great success in paclitaxel extraction technology In cooperation with Tsinghua University and Jiangnan University, the company adopts a new extraction and purification process and semi synthesis process for Taxus chinensis var mairei, which not only fully extracts taxol in free state, but also deeply develops taxanes to maximize the added value of its products On September 28 last year, Taxus taxol refinery was officially put into operation The factory has built 28800 square meters of standard plant in strict accordance with GMP standard, and has the most advanced automatic production line in China At present, paclitaxel raw materials have been exported to Europe and South America In September this year, paclitaxel preparation plant will be put into operation The first phase of new sterile preparation workshop will purchase first-class production equipment and inspection instruments at home and abroad After completion, it can produce various specifications of anti-tumor drug injection and freeze-dried powder injection, with an annual output of 6 million pieces, which can meet the needs of 250000 cancer patients Taxus, also known as yew, also known as cedar It is a shallow root plant The main root is not obvious and the lateral root is developed It is recognized as a rare natural anti-cancer plant on the verge of extinction in the world It is an ancient tree species left by Quaternary glaciers, which has a history of 2.5 million years on the earth Due to the slow growth and poor regeneration ability of Taxus under natural conditions, there has not been a large-scale raw material forest base of Taxus in the world for a long time Due to the unique anticancer mechanism of taxol, Dr Broder, director of the National Cancer Research Institute, said that taxol is a new anticancer drug with good curative effect and small side effects on a variety of cancers after adriamycin and cisplatin for 15 years Since the 1980s, the United States, Britain, Russia, South Korea and China have carried out in-depth research The United States took the lead in applying research results to clinical medicine and achieved remarkable clinical effects in the treatment of various cancers Since then, human beings have made new breakthroughs in the field of anti-cancer So far and for a long time to come, the most favorable weapon for human to fight against cancer is paclitaxel.