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On September 13, 2021, Legend Biotech announced that based on the IND application approved by the US FDA, it will start a phase 1 clinical trial of the cell therapy LB1901 under investigation for the treatment of relapsed/refractory peripheral T cell lymph in adults Tumor (PTCL), or skin T-cell lymphoma (CTCL)
TCL is a group of heterogeneous lymphoid malignancies
This open-label, multi-center phase 1 trial will evaluate the safety and tolerability of LB1901 in patients with relapsed/refractory PTCL or relapsed/refractory CTCL expressing CD4, and determine the optimal dose
Image source: Legendary Bio's official website
Reference materials:
[1] Legend Biotech Begins Phase 1 Clinical Trial in the US to Evaluate Investigational Anti-CD4 CAR-T Therapy for Relapsed or Refractory T-Cell Lymphoma.
(The original text has been deleted)