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TAND: The relationship between blood glucose variability and clinical outcomes in patients with acute stroke

 Last Update: 2021-10-20
 Source: Internet
 Author: User

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Background and purpose: Post- stroke hyperglycemia is a common phenomenon in the acute phase of stroke, and is considered to be an independent predictor of poor clinical prognosis for ischemic stroke and hemorrhagic stroke
.

Therefore, intensive treatment of hyperglycemia is expected to improve clinical prognosis

Post- stroke hyperglycemia is a common phenomenon in the acute phase of stroke.

Results: 62 cases of acute stroke patients were enrolled [48 cases of ischemic, 14 cases of hemorrhagic disease, median NIHSS score of 9 points (IQR: 3-16), mean age (65±10) years, female: 47% , Non-diabetic patients: 79%]
.

Before and after adjusting for potential confounding factors, GV with higher mean absolute blood glucose was associated with a lower probability of neurological improvement during hospitalization (OR: 0.

Table 1 Univariate Logistic regression analysis describing the relationship between GV index and 3-month functional prognosis

Table 2 describes the univariate and multivariate logistic regression analysis of the relationship between GV index, baseline characteristics, and complications during hospitalization and the likelihood of neurological improvement
.

Conclusion: The larger GV of acute stroke patients may be related to the lower probability of neurological improvement during hospitalization
.

There is no correlation between GV index and 3-month clinical outcome

The larger GV of acute stroke patients may be related to the lower probability of neurological improvement during hospitalization

Palaiodimou L, Lioutas VA, Lambadiari V,et al.

Glycemic variability of acute stroke patients and clinical outcomes: a continuous glucose monitoring study.
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