Talk about sex change?

Sexually transmitted diseases or sexually transmitted diseases (STDs), also known as STDs, refer to a group of infectious diseases that are transmitted primarily through sexual contact, sexually-like behavior, or indirect contact
.

The more common types of STDs are gonorrhea, syphilis, non-gonococcal urethritis, condyloma acuminatum, chlamydia trachomatis, chancroid, genital herpes, trichomoniasis, hepatitis B and AIDS
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STD can cause infertility, premature birth, premature rupture of membranes, and neonatal death, and it can spread among the population, endangering social security
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Introduction of three main infectious pathogens: Relevant studies reported that 40% to 50% of non-gonococcal urethritis is caused by Chlamydia trachomatis (CT), and 20% to 30% is caused by Ureaplasma urealyticum (UU).
Caused by trichomoniasis, herpes simplex virus, hepatitis virus, Candida albicans, foreskin bacillus, etc.
, transmitted through sexual contact or sexual behavior, the incidence of gonococcal urethritis is higher than that of gonococcal urethritis, which is one of the common sexually transmitted diseases
.

STD detection methods: There are many types of STD detection items on the market.
At present, the main methods are single inspection, double inspection and triple inspection.
You should first determine the type of possible patient, determine the scope, and then test.
It is very easy to be misdiagnosed, and multiple tests are particularly important
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STD detection mainly includes smear microscopy, culture method, colloidal gold and nucleic acid detection methods
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As shown in Table 1: Table 1: STD detection methods The domestic UU/CT/NG triple inspection and certificate reporting enterprises summarize Chlamydia trachomatis (CT), Ureaplasma urealyticum (UU), Neisseria gonorrhoeae ( Neisseria gonorrhoeae, NG) is a common genitourinary tract infection pathogen with a high infection rate in China
.

At present, the UU/CT/NG triple inspection and certification products on the market are still mainly based on the PCR-fluorescent probe method, as shown in Table 2: Table 2: Summary of domestic UU/CT/NG triple inspection and certification enterprises December 2021 , The First Affiliated Hospital of Xiamen University published "Characteristics and correlation analysis of Ureaplasma urealyticum, Chlamydia trachomatis and Neisseria gonorrhoeae infection in patients with urogenital infection" in "Clinical Rational Drug Use".
Urine or secretion samples of patients were amplified, and the infection status of UU, CT and NG, and the detection of single infection and mixed infection were analyzed
.

As shown in Table 3: Table 3: Test results of single and mixed infection in NG, CT, UU positive patients [cases (%)] A total of 12145 urine samples and 6290 secretion samples were collected from 18435 patients; 382 NG positive patients (detection rate 2.
07%), 2552 CT positive specimens (detection rate 13.
84%), and 8856 UU positive specimens (detection rate 48.
04%)
.

Studies have shown that UU has the highest detection rate in patients with suspected urogenital system infection, and it is necessary to strengthen UU screening to guide clinical diagnosis and treatment
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Summary In summary, rapid and effective prevention and control strategies should be formulated to improve the rate of prenatal and postnatal care and delay the occurrence of sexually transmitted diseases
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Novizan provides nucleic acid testing raw materials for STD joint inspection: References: [1] Xuan Binbin, Tan Meiyu, Sun Hanxiao, Sheng Huiming.
Analysis of mixed infection of human papillomavirus, Ureaplasma urealyticum, Chlamydia trachomatis and Neisseria gonorrhoeae in Changning District, Shanghai［J］．Laboratory Medicine, 2020, 35( 9) : 859 - 863．[2] Xie Jing, Yan Caixia, Liu Zhimin, et al.
Detection and clinical significance of Mycoplasma genitalium and Ureaplasma urealyticum in cervical secretions of patients with recurrent spontaneous abortion [J].
Contemporary Medicine, 2016, 22(10) : 48 - 49.
[3] Liu Lun.
The characteristics and correlation analysis of Ureaplasma urealyticum, Chlamydia trachomatis and Neisseria gonorrhoeae in patients with urogenital infection[J].
Clinical Rational Drug Use, 2021, 12(14) : 157 - 159.
[4] The 10th China Maternal and Child Health Development Conference, West China Securities Research Institute.
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