Take stock: A selection of BMJ studies on September 12, 2020.

The effects of Lidokain injections on the prognosis of chronic Achilles tendon lesions in adults Doi: https://doi.org/10.1136/bmj.m3027 Researchers recently examined the effects of non-corticosteroid high-volume injections as routine care aids on the prognosis of chronic Achilles tendon lesions in adults.
involved 80 adult patients with chronic Achilles tendon lesions, 39 of whom received high-volume injections of non-corticosteroids and 41 received placebos.
all participants received a 24-week routine exercise intervention, a 50mL high-volume physiological saline and lidokain injection in the high-volume injection group, and a 2 ml physiological saline and placebo injection in the control group.
end of the study was a pain and function assessment (VISA-A) at 24 weeks, with secondary results including patient satisfaction, exercise recovery, and so on.
-A score in the high-dose injection group increased from 40.4 points at the baseline to 59.1 points at 24 weeks, and the placebo group increased from 36.9 to 58.5 points.
the follow-up, the difference in VISA-A scores between groups was not significant (the difference between the adjusted 24-week groups was 0.5 points).
At 24 weeks, the satisfaction rate was 57% in patients in the high-dose injection group, 49% in the placebo group, 52% in the high-dose injection group, 61% in the placebo group, and no significant differences between the other secondary outcome groups.
. The risk of cardiovascular disease increased significantly in young people with hypertension: https://doi.org/10.1136/bmj.m3222 Researchers conducted a systematic review and meta-study that examined the association between blood pressure and cardiovascular event risk in young people.
study included a total of 17 observational queues, including about 4.5 million young people, who followed them for an average of 15 years.
study found that young people with normal blood pressure had an increased risk of cardiovascular events (relative risk 1.19) compared to adults with optimal blood pressure.
A progressive association was found between the blood pressure category and the increased risk of cardiovascular events (high normal blood pressure: relative risk 1.35; grade 1 hypertension: 1.92; level 2 hypertension: 3.15), with similar observations of coronary heart disease and stroke.
: Doi: https://doi.org/10.1136/bmj.m2651 Researchers recently quantified the predicted value of accidental weight loss (WL) for tumor diagnosis based on the patient's age, sex, smoking status and clinical characteristics (symptoms, signs, and abnormal blood test results).
among 63,973 adults who accidentally lost weight, 37? 215 (58.2%) were female, 33,167 (51.8%) were 60 years of age or older, and 16,793 (26.3%) had smoked.
908 (1.4%) were diagnosed with cancer within six months, of whom 882 (97.1%) were over 50 years of age.
total of 10 tumor risk factors associated with accidental weight loss in men and 11 in women.
Among the tumor risk factors for accidental weight loss in men, the lowest risk factor was non-cardiac chest pain (1.86), the highest risk factor was abdominal lumps (6.10), and among the tumor risk factors for women who accidentally lost weight, the lowest risk factor was low back pain (1.62) and jaundice (20.9).
tumor-related abnormal blood test results included low albumin levels (4.67), plate plate plate abnormalities (4.57), abnormal blood calcium (4.28), abnormal white blood cell totals (3.76) and elevated C-reactive proteins (3.59).
: DOI for children and adolescents in the UK: https://doi.org/10.1136/bmj.m3249 Researchers recently examined laboratory-proven severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-Cov-2) infects the clinical characteristics of hospitalized children and adolescents, and explores risk factors for critical care, mortality, and multisyscular inflammatory syndrome (MIS-C) in children and adolescents associated with coronavirus disease (COVID-19) in 2019.
researchers collected data from 260 hospitals in England, Wales and Scotland between 17 January and 3 July 2020, during which 651 patients under the age of 19 were treated in 138 hospitals for neo-corona pneumonia, with the main endpoints of the study being critical care, hospital mortality and MIS-C morbidity. the average age of
children is 4.6 years, of which 35 per cent (225 cases) are children under 12 months of age, 56 per cent are men, 57 per cent are white, 12 per cent are Black, 10 per cent are black and 42 per cent (276) have other common diseases.
18 per cent of children received intensive care (116 cases).
of the 627 children in the hospital, 6 (1%) died in hospital, all with underlying co-diseases.
11% of children who met the WHO-MIS-C definition, as early as mid-March, had a higher risk of MIS-C in children under the age of 10-14 (3.23) and black children (2.82) after multi-factor adjustments The risk of intensive care in children was 5 times higher than in the general population (73% vs 15%), and there was no significant increase in the risk of fatigue, headache, muscle pain, sore throat, swollen lymph nodes and platelet counts of less than 150 x 109/L in children with MIS-C, but no deaths occurred in children with MIS-C.
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