Successful culture of somatic cloned cattle by China and France (11.21)

OA show ('918 '); Paris, Nov 15, Xinhua News (reporter Lu Suyan) a somatic cloned cow carefully cultivated by Chinese and French researchers was successfully born by caesarean section at the National Institute of Agronomy in France on Nov 15 This is the first time that Chinese and French scientists have successfully bred a cloned bovine with somatic cells by using the injection nuclear transfer technology invented by Chinese scientists, and also the first cloned bovine without adopting the technology of cloning "Dolly sheep" in the world The calf is a female It comes from the ear epithelial cells of an adult cow Its birth weight is 51 kg and all health indicators are normal According to Zhou Qi, Institute of developmental biology, Chinese Academy of Sciences, who participated in the research, the process of introducing exogenous genetic material can be simplified from two steps to one step by replacing the electric fusion method of cloned Dolly sheep with the method of injecting nuclear transfer In addition, compared with electrofusion, it can not only shorten the production cycle and improve the efficiency of cloning, but also control the activation time of cloned embryos and adjust their cell cycle Before this, many laboratories in the world had tried to replace the electrofusion technology with other technologies, but the development of cloned embryos stopped at the early stage of pregnancy, which ended in failure The birth of this somatic cloned cow is another successful cooperation between China and France in the field of cloning research On July 30 last year, Chinese and French scientists successfully cultivated the first adult somatic cell clone mouse by using the mouse embryo micromanipulation injury resection invented by Chinese scientists and the molecular biology technology mastered by French researchers, which confirmed the world's first experiment of reproduction of adult somatic cell clone mouse and solved the problem that puzzled scientists in the field of cloning for a long time Their research has been published in the British Journal clone in September this year In May this year, scientists of the two countries cooperated once again to successfully cultivate the first embryonic stem cell cloned mouse Up to now, the mouse has normally produced three generations, including its natural reproduction offspring with another female somatic cell cloned mouse The researchers said that if the cloning of mice by injection of nuclear transfer technology is still in the basic research stage of promoting laboratory research, then the successful cloning of somatic cattle by this method will further push the cloning technology to practical use, because it brings hope for further improving the cloning efficiency and success rate, which makes a large number of cloning of excellent breeding animals no longer an illusion At the same time, it also means that it will help to promote the leap of animal husbandry production Rad (author:)