Study reveals mechanisms that increase "abdominal fat" around organs as they get older
-
Last Update: 2020-06-07
-
Source: Internet
-
Author: User
Search more information of high quality chemicals, good prices and reliable suppliers, visit
www.echemi.com
recently published in the journal Cell me
tabolism, researchers from Yale University revealwhy that "abdominal fat" around organs increases as we ageThe findings could provide new treatment possibilities for improving metabolichealthy(http://, reducing the risk of diseases such as diabetes and atherosclerosis caused by inflammationPrevious work has found that as we age, the body's ability to generate energy by burning belly fat decreasesAs a result, the fat around the internal organs of the elderly increasesDixit's lab found that the immune cells (called macrophages) necessary for the fat burning process are still active, but their totals are declining as belly fat increases with ageThe new study found that as animals age, fat B cells in belly fat proliferate unexpectedly, leading to increased inflammation and decreased metabolic levelsWhen they work properly, some B-cells expand as needed to protect the body from infection and then shrink to the baselineBut as they get older, they don't shrink in belly fatThe researchers found that fat B cells amplify by receiving signals from nearby macrophagesThe researchers found that by reducing macrophages signaling and removing fat B cells, they can reverse the amplification process and prevent age-induced metabolic health decline
This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only.
This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of
the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed
description of the concern or complaint, to
service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content
will be removed immediately.
