Study on the treatment of diabetic lower extremity angiopathy with Ginkgo biloba extract and alprostadil

Recently, researchers from the Affiliated Hospital of Air Force Aviation Medical Research Institute published a paper to observe the effect of Ginkgo biloba extract combined with alprostadil on diabetic lower extremity vascular disease It was pointed out that Ginkgo biloba extract combined with alprostadil can effectively improve the symptoms of lower limbs of diabetic patients, expand blood vessels, and have a long-lasting and stable effect with low adverse reaction rate This article was published in the first issue of the Journal of modern integrated Chinese and Western medicine in 2014 110 patients with diabetic lower extremity angiopathy were randomly divided into two groups: observation group (alprostadil 10 μ g / D IV + Ginkgo biloba extract 80 mg twice a day for 12 weeks) and control group (alprostadil 10 μ g / D IV) The clinical symptoms were recorded before and 4 weeks and 12 weeks after treatment, the ankle brachial index (ABI) and the blood flow of dorsalis pedis artery were measured, and the blood pressure, glycosylated hemoglobin, blood lipid, liver function, renal function, clotting time and other indexes were examined After 4 weeks of treatment, the clinical symptoms, ABI value, peak velocity and blood flow of dorsalis pedis artery in the two groups were significantly improved; there was no significant difference between the two groups At the 12th week of treatment, the clinical effect of the observation group was good, and there was no significant change in ABI and hemodynamic monitoring indexes of dorsalis pedis compared with that of the 4th week; the effect of the control group was significantly decreased compared with that of the 4th week, and there was no significant difference in clinical performance, ABI and hemodynamic indexes of dorsalis pedis compared with that before treatment.