Study on the acute toxicity and in vivo antibacterial activity of the extract of Baihua jiuliming
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Last Update: 2015-11-10
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Source: Internet
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Author: User
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Recently, researchers from Guangxi Vocational College of health and technology published papers to study the acute toxicity and antibacterial effect of extract of Baihua jiuliming, a strong medicine It was pointed out that the extract of Baihua jiuliming, a strong medicine, was low toxic and safe to take in large doses It had a certain in vivo protective effect on mice infected with Staphylococcus aureus and was worthy of further research and development This article was published in the 25th issue of the Journal of modern integrated Chinese and Western medicine in 2015 Sequential method was used to determine the acute toxicity of baihuajiuliming water and alcohol extract on mice, and animal protection experiment was used to determine the protective effect of different doses of baihuajiuliming water extract on mice infected with Staphylococcus aureus and Klebsiella pneumoniae The LD50 of baihuajiuliming water extract was (134.17 ± 9.043) g crude drug / kg, 95% confidence interval was (125.127143.213), the LD50 of alcohol extract was (107.37 ± 17.665) g crude drug / kg, 95% confidence interval was (89.705125.035) The water extracts of Baihua jiuliming, a strong medicine, 6.7 g / kg, 13.4 g / kg and 26.8 g / kg can reduce the mortality and prolong the average survival time of mice infected with Staphylococcus aureus.
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