Studies have revealed that neurosympathic signs in patients with schizophrenia are associated with abnormal brain-brain function connections

Neurom software signs are important biomarkers of schizophrenia.
traditional definition, neurosympathic signs are considered to be a group of mild abnormalities of the nervous system, mainly reflected in the lack of motion coordination, sensory integration, inhibition function, but the lack of behavioral level defects corresponding to the brain region positioning.
studies have shown that the defects of neurosoppletic signs are closely related to specific networks of brain functions.
, previous studies have focused only on the brain's functional connectivity mechanisms for neurosoppy movement coordination deficiencies.
has been studied to find that the brain is an important node of a variety of functional networks, the abnormality of these functional networks will further cause schizophrenia patients cognitive and sensory processing defects.
, however, few studies have further explored the relationship between fission-brain function connectivity and sensory integration deficiencies in patients with schizophrenia.
The team of Neuropsychology and Applied Cognitive Neuroscience (NACN), led by Chen Chuxiao, a researcher at the Mental Health Key Laboratory of the Institute of Psychology of the Chinese Academy of Sciences, found in previous studies that schizophrenia patients and their unsophicated siblings had a lack of activation of the microcephaly during sensory integration processing, and that the neural activation was significantly inheritable.
based on existing research results, Chen Chu overseas Chinese team recently conducted a study to further explore the relationship between neurosophageal signs and the function of the small brain-brain resting state in 51 patients with schizophrenia and 50 healthy controls.
study found that the functional connection between the microcephaly and the lower frontal and wedge lobes in patients with schizophrenia was significantly positively corred with neurosophageal defects, and the functional connections between the microcephaly and the lower temporal back were significantly negatively corred with neurosophageal defects.
a functional connection between the microcephaly-frontal loin, which is significantly associated with neurosoppletic signs, was further found to be significantly positively related to negative symptoms in patients.
, the researchers repeated similar findings in a separate sample that included 34 pairs of schizophrenic patients and healthy controls.
The study found that the neural brain and its abnormal functional connections to the brain play an important role in neurosympathic signs and negative symptoms in people with schizophrenia, suggesting that abnormal cer cerebral-brain functional connections may be a potential neural mechanism for sharing neurosophageal signs and negative symptoms in patients with schizophrenia.
, inheritable brain activation under sensory integration processing may also be a potential internal esophation of schizophrenia.
results were published online online in Schizophrenia Bulletin.
research is supported by the National Key Research and Development Program, the Beijing Science and Technology Leadership Project, the Mental Health Key Laboratory of the Institute of Psychology, and the Philip K.H. Wong Fund.
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