 Home > Active Ingredient News > Blood System > STTT: The domestic multi-center study ORIENT-4 confirmed that the PD-1 inhibitor sintilimab (sintilimab) is effective and tolerable in patients with relapsed/refractory extranodal NK/T cell lymphoma (r/r ENKTL) good

STTT: The domestic multi-center study ORIENT-4 confirmed that the PD-1 inhibitor sintilimab (sintilimab) is effective and tolerable in patients with relapsed/refractory extranodal NK/T cell lymphoma (r/r ENKTL) good

 Last Update: 2022-01-08
 Source: Internet
 Author: User

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Extranodal natural killer (NK)/T-cell lymphoma (ENKTL) is a highly aggressive non-Hodgkin lymphoma (NHL) subtype with a high incidence in Asia and Latin America

Lymphoma infection immunity

ORIENT-4 is a multi-center, single-arm, phase 2 clinical trial (NCT03228836)

From August 31, 2017 to February 7, 2018, 34 patients were screened , and 28 patients were finally enrolled

Screening for stem cells

As of February 28, 2020, the median follow-up time was 30.

The median follow-up was 30.

Twenty-seven patients (96.

Diabetes Digestion

In summary, the ORIENT-4 study shows that the PD-1 inhibitor sintilimab (sintilimab) is effective and well tolerated in patients with relapsed/refractory extranodal NK/T cell lymphoma (r/r ENKTL)

Original source:

Tao R, Fan L, Song Y, Hu Y, Zhang W, Wang Y, Xu W, Li J.

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