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Cerebral venous thrombosis (CVT) is a cerebral vascular disease can occur at any age, accounted for 0.
5% of all strokes
.
The initial report on CVT, inferred from the autopsy series, indicated that the incidence of CVT was 1 to 2 cases per 1000 000 people
Thrombotic vascular
A recent population-based study conducted in the Netherlands observed a total incidence rate of 13.
2 cases per 1,000,000 people per year, with a higher proportion of women
.
In most cases, the pathological conditions that lead to cerebral venous circulation thrombosis are related to non-suppurative CVT, and purulent CVT may be a complication of head trauma, caused by the local extension of intracranial sinus infection
Infect
In recent years, the widespread use of noninvasive neuroimaging has made it possible to diagnose and detect clinically less severe CVT cases, which is also the reason for the increase in the incidence of CVT
.
.
diagnosis
Regarding the in-hospital mortality rate of CVT, there are currently some controversial data
.
Although CVT was previously associated with a poor prognosis, recent research reports show that the mortality rate after the index event at discharge ≈ 4%
They used the clinical modification codes 325, 671.
5, and 437.
6 of the ninth edition of the International Classification of Diseases to determine the primary and secondary discharge diagnosis of purulent/non-suppurative CVT
A total of 1,718 patients were hospitalized for CVT (1147 women-66.
8%; 810 purulent and 908 non-suppurative CVTs, 47.
1% and 52.
9%, respectively), of which 134 patients (7.
8%) also had ICH
.
The total incidence of CVT was 11.
6 cases per 1 million inhabitants, and the sex-specific incidence rates for women and men were 15.
1 and 7.
8 per 1 million inhabitants, respectively
.
During the observation period, the incidence of CVT in women increased significantly (P=0.
007), and the highest incidence was between 40 and 44 years old (27.
0 cases per 1,000 000)
.
007), and the highest incidence was between 40 and 44 years old (27.
0 cases per 1,000 000)
.
The in-hospital CFR was 3%, and there was no difference between purulent/non-suppurative CVT
.
Compared with patients without ICH, patients with ICH had higher in-hospital CFR (7.
5% vs.
2.
7%; OR=2.
96 [95% CI, 1.
45-6.
04])
.
The CFR in the hospital gradually increased with the increase of the Charlson comorbidity index (P=0.
003)
.
Age (OR=1.
The important significance of this study lies in the discovery: The incidence of CVT is comparable to the incidence registered in population-based research reports after 2000
.
The incidence of CVT in women increases over time
The incidence of CVT is comparable to the incidence registered in population-based research reports after 2000
Original source:
Rezoagli E, Bonaventura A, Coutinho JM, et al.
Incidence Rates and Case-Fatality Rates of Cerebral Vein Thrombosis: A Population-Based Study.
Stroke.
Published online August 10, 2021.
doi:10.
1161/STROKEAHA.
121.
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