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Intravascular embolization plus non-shunt stents (laser cutting stents, braided stents, etc.
Blood vessel
However, thrombotic embolic events is the most common cause of neurological disease after interventional procedures
Thrombosis is very important for reducing thromboembolic events in the treatment of patients undergoing cerebral aneurysm stenting
A considerable number of patients with high platelet reactivity during treatment have insufficient platelet suppression, and the risk of hemorrhagic embolism is increased
At present, there are few prospective randomized controlled trials on the monitoring of platelet function in cerebrovascular diseases
A randomized controlled trial showed that compared with standard antiplatelet therapy, changing antiplatelet therapy under the guidance of platelet function monitoring can reduce the frequency of thromboembolic events without increasing the amount of bleeding.
They conducted a randomized, open-label, parallel-group, evaluator-blinded trial
The second monitoring was performed on medication-adjusted patients 14 days after randomization
A total of 314 patients were included (157 in each group)
Compared with the conventional group, the frequency of ischemic stroke in the monitoring group was lower (4.
Stroke
The safety results occurred in the monitoring group (7.
Antiplatelet therapy under the guidance of platelet function monitoring reduced the thromboembolic events of patients with unruptured intracranial aneurysms after stent placement, and significantly enhanced minor or very few bleeding events, but no major bleeding events
Antiplatelet therapy under the guidance of platelet function monitoring reduces thromboembolic events in patients with unruptured intracranial aneurysms after stent placement.
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