stroke: Tiantan Hospital: Malnourished people have worse outcomes for stroke

In China, the brain stroke is the leading cause of death and disability
.

2018, China cerebral vascular disease crude death rate was 149.

Stroke blood vessel

Malnutrition is a noteworthy risk factor, which leads to poor functional outcomes and higher mortality in stroke patients
.

In addition, nutritional status at admission is an independent predictor of pneumonia and gastrointestinal bleeding during hospitalization

The incidence of malnutrition in stroke patients varies greatly from country to country, and the latest data are lacking in China

Screening consensus diagnosis

These objective malnutrition scores have been used in patients with heart failure, atrial fibrillation, acute coronary syndrome, as well as cancer and surgery
.

Recent studies have used objective scores to assess the risk of malnutrition in stroke patients, and reported that the risk of malnutrition at admission is associated with poor short-term outcomes

In the past few years, several prognostic models have been developed
.

Lausanne Acute Stroke Registration and Analysis (ASTRAL) and iScore have been externally verified to predict the adverse clinical outcome of stroke patients in China

In this way, dGuitao Zhan and others of Tiantan Hospital used the data of the third phase of China’s National Stroke Registry to investigate the incidence of malnutrition risk at admission and the relationship between nutritional risk and adverse clinical outcomes.

This is a national A sexual, large-scale, and prospective cohort of Chinese ischemic stroke patients

They used GNRI, CONUT, and PNI to explore the predictive power of malnutrition risk for long-term AIS outcomes

Based on the controlled nutritional status score, the elderly nutritional risk index and the prognostic nutritional index, 5.

89%, 5.
30% and 1.
95% of the AIS patients of the third China National Stroke Registry were confirmed to have moderate to severe nutrition.
Bad risk

During the 1-year follow-up, 1143 participants (13.
5%) experienced death or major disability
.

After adjusting for traditional risk factors, the risk of moderate to severe malnutrition is related to the high risk of compound events (the odds ratio of the controlled nutritional status score is 2.

The odds ratio of the elderly nutritional risk index was 2.
10 [95% CI, 1.
63-2.
69]; the odds ratio of the prognostic nutrition index was 3.
36 [95% CI, 2.
33-4.
84]; all P<0.
01)
.

Adding three malnutrition scores to different predictive scales (iScore and Lausanne acute stroke registration and analysis) improved the predictive ability of long-term adverse outcomes verified by the comprehensive discrimination index (all P<0.
05)
.

The important significance of the study is that it found that the incidence of moderate or severe malnutrition risk in Chinese AIS patients is between 1.
95% and 5.
89%
.
The risk of malnutrition in AIS patients is associated with an increased risk of long-term death and major disability
.
This study provides evidence to support the prognostic significance of objective malnutrition scores after AIS
.

The incidence of moderate or severe malnutrition risk in Chinese AIS patients ranges from 1.
95% to 5.
89%
.

Original source:

Zhang G, Pan Y, Zhang R, et al.
Prevalence and Prognostic Significance of Malnutrition Risk in Patients With Acute Ischemic Stroke: Results From the Third China National Stroke Registry.
Stroke.
Published online October 14, 2021:STROKEAHA.
121.
034366.
doi: 10.
1161/STROKEAHA.
121.
034366

Prevalence and Prognostic Significance of Malnutrition Risk in Patients With Acute Ischemic Stroke: Results From the Third China National Stroke Registry.
Stroke.

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