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Although there is increasing evidence that the cerebellum and cerebral amyloid vascular -related disease (CAA), but the surface of iron deposition cerebellum is not considered a disease marker
.
Recently, a research article was published in Stroke, an authoritative journal in the field of cardiovascular diseases.
The study aims to investigate the frequency of iron deposition on the cerebellar surface of patients with sporadic and Dutch hereditary CAA and patients with deep penetrating artery disease-related intracerebral hemorrhage and its relationship with hemorrhagic The relationship between MRI markers
.
The researchers recruited patients from three prospective 3 Tesla magnetic resonance imaging studies and scored iron deposition and bleeding
.
Cerebellar ironosis is determined to be a low-intensity linear signal loss (black) in a susceptibility-weighted or T2*-weighted magnetic resonance imaging examination, which results in at least one lobe of the cerebellar cortex (including the vermis)
The researchers included 50 Dutch-type hereditary CAA subjects (average age 50 years), 45 sporadic CAA patients (average age 72 years), and 43 patients with deep penetrating artery disease-related intracerebral hemorrhage (average age The age is 54 years old)
.
Five of the 50 Dutch type hereditary CAA patients (10%[95%CI=2-18]) had iron deposits on the cerebellar surface, and 4/45 (9%[95%CI=1-17]) had sporadic CAA patients have iron deposits on the cerebellar surface, and 0 of 43 patients with deep penetrating artery disease-related intracerebral hemorrhage (0%[95%CI = 0-8]) have iron deposits on the cerebellar surface
It can be seen that iron deposition on the surface of the cerebellum may be a new sign of CAA
.
.
Original source:
Original source:Emma A.
