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Although zinc has antioxidant and anti-inflammatory effects, there is a lack of prospective studies exploring the relationship between zinc content and the risk of ischemic stroke
.
Recently, the heart blood vessels published a research article on the disease areas prestigious journal Stroke, the study aimed to assess the association between serum zinc content of the US population, and the incidence of ischemic stroke
.
The researchers used a case cohort study nested in the cohort for the geographical and ethnic differences in stroke, randomly selected participants from the cohort for the geographical and ethnic differences in stroke to form a sub-cohort (n=2346), and included the data as of September 2012 Of all ischemic stroke cases (n=660), 62 of them overlapped in the sub-cohort
.
The researchers measured the subjects' serum zinc levels at baseline, and used the Barlow-weighted Cox proportional hazards regression model to calculate the multivariate adjusted hazard ratio and 95% CI for ischemic stroke corresponding to the serum zinc levels
The median zinc content of the study participants was 121.
19 µg/dL (interquartile range 104.
86-140.
39 µg/dL)
.
After adjusting for potential confounding factors, serum zinc content was negatively correlated with the incidence of ischemic stroke (the hazard ratio of quartile 4 compared to quartile 1 was 0.
Serum zinc content is negatively correlated with the incidence of ischemic stroke, especially in women, indicating that low zinc content may be a risk factor for ischemic stroke
Original source:
Lindsey Mattern.
et al.
Serum Zinc Levels and Incidence of Ischemic Stroke: The Reasons for Geographic and Racial Differences in Stroke Study .
stroke.
2021.
