Stroke: Relationship between hypersensitive myocardial troponin T and cognitive function in patients with ischemic stroke

In a recent study published in the journal Stroke, an authoritative journal on cardiovascular disease, researchers looked at whether highly sensitive myocardial troponin T (hs-cTnT), a specific biomarker of myocardial injury, was associated with cognitive function in patients with first mild to moderate ischemic strokeresearchers used data from the Berlin Stroke Prospecting Queue (PROSIS-B)Cognitive function was evaluated at baseline through Mini psychological state checking, and cognitive state correction was conducted after 1 to 3 years of follow-upPatients were classified by the quartile level of hs-cTnTThe researchers performed a broad linear regression to calculate the risk ratio for cognitive impairment (Mini's mental state test score 27; the cognitive state correction for telephone interview scores,32)The researchers used a linear hybrid model to estimate the correlation between hs-cTnT and cognitive function over timeresearchers included 555 patients (average age of 67 years, 62 percent male, the Median stroke scale score of the National Institutes of Health was 2 (1-5 in quartile range), 40 percent above the reference limit, and 28 percent of baseline cognitive impairmentThe highest quartile of hs-cTnT has a lower baseline Mini mental state assessment score and lower incidence of cognitive impairment compared to patients with the lowest quartile (medians 27 vs29 and 15.3% vs43.0%, with an adjustment risk ratio of 1.76 (95% CI is 1.07-2.90)If any difference is anyindication, it appears that cognitive function improved in all groups, but the highest quartile of hs-cTnT continued to decrease in the cognitive state correction score (adjusted beta to -1.33 (95% confidence interval of -2.65 to -0.02) compared to patients with the lowest quartilethus showed that higher hs-cTnT was associated with higher prevalence of cognitive impairment at baseline and lower cognitive improvement during 3 years of follow-up in patients with mild to moderate ischemic stroke without dementia