Stroke: Hemorrhage in children with cerebral hemorrhage is enlarged

Significant hemorrhage enlargement (sHE) is a predictive factor for poor prognostics in adults with cerebral hemorrhage (ICH), but is still rarely reported in children.
A recent study published in the authoritative journalStroke on Cardiovascular Disease, in a large team study, researchers looked at the prevalence of sHE and assessed its relationship to clinical outcomes, as well as its clinical imaging predictive factors in children.
researchers screened children admitted to level 4 health pediatric hospitals between January 2000 and March 2020.
were limited to children who had two computer fault scans within 72 hours of the ICH attack and were clinically followed up within a few months.
is defined as an increase of 6 cc or 33% in ICH volume from the baseline in subsequent computer scans.
researchers assessed clinical outcomes at 12 months using King's Children's Head Injury Outcome Scale and defined a score of ≥5 for better outcomes.
52 children met the criteria for selection, of whom 8 (15%) showed SHE and 18 (34.6%) had some degree of dilation.
of coagulation dysfunction occurs more frequently in children with sHE (25.0% vs. 2.3% ;P x 0.022).
after multivariate adjustment, only the presence of clotting disorders at baseline is independently associated with sher (adjusted ratio of 14.4 (95% CI is 1.04-217) ;P=0.048).
was independently associated with poor prognosmation (King's Children's Brain Injury Outcome Scale s.lt;5A, with a ratio of 5.77 (95% CI of 1.01-38.95) ;P=0.043).
, sHE is a common manifestation of hospitalization in children with ICH, even more so in children with clotting dysfunction.
because sHE is closely related to poor clinical outcomes, these results require baseline clotting tests and challenge the plan to perform repeated brain computer fracture scans on admitted ICH children.