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In planning public health measures, it is particularly important to assess whether there is a causal link between changeable risk factors and stroke risk, but it may be difficult to determine causation from epidemiological data.
, researchers aim to assess lifestyle changes, including education, smoking and body mass index (BMI) as risk factors for ischemic stroke and its subtypes and hemorrhagic strokes, in a study published recently in the leading journal of cardiovascular disease.
researchers used a two-sample and multivariate Mendel randomization method to assess the causal effects of 12 lifestyle factors on stroke risk and whether they were independent.
found a negative correlation between genetically predicted years of schooling and ischemic stroke, aortic stroke and small blood vessel stroke, and cerebral hemorrhage.
predicted smoking, body mass index and waist-to-hip ratio were associated with ischemic stroke and aortic stroke.
, body mass index and the effects of smoking on ischemic stroke are independent.
In turn, the results of the study support the hypothesis that low levels of education, smoking and obesity increase the risk of ischemic stroke, aortic stroke, and small blood vessel stroke, suggesting that lifestyle improvements in these risk factors will reduce the risk of stroke.
