 Home > Active Ingredient News > Study of Nervous System > Stroke: After subarachnoid hemorrhage, chronic liver injury can increase patient mortality

Stroke: After subarachnoid hemorrhage, chronic liver injury can increase patient mortality

 Last Update: 2021-09-03
 Source: Internet
 Author: User

Tags

inflammatory liver disease

cpt2 disease symptoms

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

Chronic liver disease (CLD) clinically refers to a disease process of the liver, including the gradual destruction and regeneration of liver parenchyma, leading to fibrosis and cirrhosis
.

It includes a wide range of liver diseases, including inflammation (chronic hepatitis), cirrhosis and hepatocellular carcinoma

Chronic liver disease (CLD) is an important risk factor for increased morbidity and mortality in patients with acute diseases
.

For neurosurgeons, CLD and its impact on bleeding risk is an important clinical issue

Currently, few studies have investigated the relationship between CLD and clinical outcomes in patients with aneurysmal subarachnoid hemorrhage (aSAH)
.

In this way, Yu Zhang and others of West China Hospital of Sichuan University evaluated the relationship between CLD and mortality, and investigated whether the model of end-stage liver disease (MELD) score is an independent predictor of mortality in patients with CLD and aSAH
.

In this retrospective cohort study, they analyzed consecutive aSAH patients admitted to West China Hospital from 2009 to 2019
.

The main result is all-cause mortality in the hospital

This study included 6228 cases of aSAH, of which 489 (7.
9%) also had CLD
.

In propensity matching analysis, compared with non-CLD, CLD was associated with increased mortality in patients with aSAH (odds ratio, 2.
04 [95% CI, 1.
43-2.
92])
.

In aSAH patients with CLD, high scores in end-stage liver disease models are still associated with increased mortality

The important significance of this study lies in the discovery: in patients with aSAH, compared with non-CLD, CLD is associated with increased mortality
.

In aSAH patients with CLD, a higher end-stage liver disease model score is associated with an increase in mortality

In patients with aSAH, CLD is associated with increased mortality compared with non-CLD

Original source:
Zhang Y, Li L, Jia L, et al.

Association of Chronic Liver Disease and Mortality in Patients With Aneurysmal Subarachnoid Hemorrhage.
Stroke.

Leave a message here

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.