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Stem cell model reproduces early human embryonic development

 Last Update: 2022-02-25
 Source: Internet
 Author: User

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According to a study published in the British "Nature" magazine on the 2nd, scientists used human pluripotent stem cells to establish a model that can be used to study the process of human embryo implantation into the uterus

Within a week of fertilization, human embryos develop cell masses called blastocysts, which implant into the uterine wall

This time, Nicholas Liveron, a researcher at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences, and his colleagues used human pluripotent stem cells to construct human blastocyst-like structures (embryoids)

The human embryoid bodies specifically adhered to hormone-stimulated endometrial cells in vitro, allowing the team to reproduce periimplantation development until day 13, the study reports

Due to the high efficiency of the model and its great scalability potential

Stem cells can reveal how organs are formed, but previous research in this area has been difficult to help us better understand the developing embryo

However, these structures, or micro-organs, often replicate some but not all of the structure and function of real organs

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This technological breakthrough is expected to provide us with new methods and new ideas for studying the early stages of human development and understanding developmental disorders, infertility and genetic diseases, and even improve the success rate of IVF

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