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Medicine Network October 21 - Does the new coronavirus mutation have an impact on vaccine research and development? At a press conference held by the State Council on the 20th, Tian Baoguo, deputy director of the Department of Social Development Science and Technology of the Ministry of Science and Technology, said that the tracking study showed that the new coronavirus mutation had no substantial impact on vaccine research and development.
Tian Baoguo said that the scientific research team has been highly concerned about the problem of virus mutation, organized more than 30 scientific research institutions nationwide to carry out follow-up research on virus mutation.
, there are nearly 150,000 genome sequences of new coronavirus in the global database, covering more than 100 countries and regions on six continents.
comparative analysis of more than 80,000 high-quality viral genome sequences showed that the virus had little variation, was within the normal range of mutation accumulation, and had no substantial impact on vaccine development.
Tian Baoguo explained, first, the current domestic and foreign vaccine research and development of antigen design mainly for the new coronavirus S protein, through the comparison and analysis of tens of thousands of new coronavirus genome sequence, found that the sequence of the new coronavirus S protein is relatively stable.
is a mutation that occurs at individual bits of the existing S protein, which has little effect on the primary structure and immunogenicity.
trials have shown that the vaccine being tested can effectively medium and mutate the new coronavirus.
, Tian Baoguo said that in the follow-up work, the scientific research team will closely track the virus mutation, timely research and judgment, for the vaccine research and development team to provide timely early warning and scientific reference.
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